There is growing interest in intranasal therapies as a tolerable and acceptable delivery route for medications proposed to treat Autism Spectrum Disorder (ASD). Nasal geometry and flow represent two factors that may moderate bioavailability and response to intranasal drugs. However, modern measures of nasal assessment such as acoustic rhinometry and rhinomanometry have not been examined in this population. The seminar will give an overview of paediatric intranasal delivery, why nasal structure and flow may be important moderators, and results from trialling modern methods of nasal assessment in a paediatric ASD cohort.
Ms Erin Madden (MBMSc)
The Autism Centre for Translational Research
Erin Madden recently completed a Masters in Brain and Mind Sciences at the University of Sydney. During this time she undertook a research placement at The Autism Centre for Translational Research (ACTR), specifically working with data from ongoing oxytocin nasal spray trials. She is currently working full time as a Research Officer at The Matilda Centre for Research in Mental Health and Substance Use.